Tri-allelic pattern at the TPOX locus: A familial study
نویسندگان
چکیده
منابع مشابه
Allelic imbalance at the HER2/TOP2A locus in breast cancer
BACKGROUND Breast cancer is a heterogeneous disease with various histological features and molecular markers. These are utilized for the prediction of clinical outcome and therapeutic decision making. In addition to well established markers such as HER2 overexpression and estrogen and progesterone receptor (ER and PR) status, chromosomal instability is evolving as an important hallmark of cance...
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OMPLEMENTATION between allelic mutants at the ad-4 (adenine-4) locus, deficient for the enzyme adenylosuccinase (adenylosuccinate AMP-lyase, C.E. 4322). was first reported in Neurospora (GILES, PARTRIDGE and NELSON 1957; WOODWARD, PARTRIDGE and GILES 1958). It was found that certain pairs of these mutants, which as a result of the absence of adenylosuccinase activity require adenine for growth,...
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Most null alleles at the nivea (niv) locus are recessive to Niv+ and, when homozygous, give white flowers rather than the red of the wild type. In contrast, the niv-571 allele is semidominant; although it gives white flowers when homozygous, very pale flowers result when this allele is heterozygous with Niv'. We showed that in heterozygotes, niv-571 acts in trans to inhibit expression of its Ni...
متن کاملAllelic interactions at the nivea locus of Antirrhinum.
Most null alleles at the nivea (niv) locus are recessive to Niv+ and, when homozygous, give white flowers rather than the red of the wild type. In contrast, the niv-571 allele is semidominant; although it gives white flowers when homozygous, very pale flowers result when this allele is heterozygous with NIV+. We showed that in heterozygotes, niv-571 acts in trans to inhibit expression of its Ni...
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The mutations of the Abruptex locus in Drosophila melanogaster fall into three categories. There are recessive lethal alleles and viable alleles. The latter can be divided into suppressors and nonsuppressors of Notch mutations. The recessive lethals are lethal in heterozygous combination with Notch. As a rule the recessive lethals are lethal also in heterozygous combination with the viable alle...
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ژورنال
عنوان ژورنال: Gene
سال: 2014
ISSN: 0378-1119
DOI: 10.1016/j.gene.2013.10.019